Is cystic fibrosis inherited from one parent or both?


Margaret Jackson   |   Member since 2012  |  10+ Answers Submitted  |  ✔ Verified

Cystic fibrosis is inherited in an autosomal recessive manner. Our genes come in pairs, with one copy inherited from each parent. If both parents are carriers there is a 1 in 4 (25 percent) chance that both will pass on the non-functioning gene, which would result in a pregnancy affected with cystic fibrosis.

The Genetics of Cystic Fibrosis. Cystic fibrosis (CF) is a genetic disease. This means that it is inherited. A child will be born with CF only if they inherit one CF gene from each parent.

how is CF passed down through families? A person must inherit 2 CF genes to have CF disease. When your child was conceived, he or she received a CF gene from both you and your partner. A child can inherit CF only if both parents carry a CF gene (that is, each parent either has CF or is a carrier) and both parents pass the CF gene on to their child.

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William Redden   |   Member since 2009  |  10+ Answers Submitted  |  ✔ Verified

Keeping this in consideration, how can a child inherit cystic fibrosis if neither parent has the disease?

Cystic fibrosis is an example of a recessive disease. That means a person must have a mutation in both copies of the CFTR gene to have CF. If someone has a mutation in only one copy of the CFTR gene and the other copy is normal, he or she does not have CF and is a CF carrier. 25 percent (1 in 4) the child will have CF.


Taylor Evans   |   Member since 2005  |  10+ Answers Submitted  |  ✔ Verified

Can you have cystic fibrosis without family history?

Yes. In fact, most couples who have a child with CF have no family history of cystic fibrosis and are surprised to learn that they carry a mutation in the CFTR gene, which causes the condition. Genes are the basic hereditary units determining an individual's traits, such as hair and eye color.


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Below is a list of answers to questions that have a similarity, or relationship to, the answers on "Is cystic fibrosis inherited from one parent or both?". This list is displayed so that you can easily and quickly access the available answers, without having to search first.

Javier Addley   |   Member since 2015  |  ✔ Verified

What happens if you are a carrier of cystic fibrosis?

Some genes have mutations in them, and do not function properly. A person with one non-functional copy of the gene is a carrier . Carriers for CF have no symptoms, but can pass the non-functioning gene on to their children. An individual must inherit two non-functioning CF genes – one from each parent – to have CF .


Boris Redwood   |   Member since 2019  |  ✔ Verified

What's the longest someone has lived with cystic fibrosis?

US and British registry data reveal the oldest patients with CF in these countries to be 82 and 79 years respectively; the oldest patient previously recorded here was 61. The woman in this case “remains stable” at age 78.


Lucas Varndell   |   Member since 2015  |  ✔ Verified

Do new lungs cure cystic fibrosis?

When medical management alone can no longer maintain lung health and physical function, a lung transplant can improve the length and quality of life for a person with cystic fibrosis . Transplantation is an important treatment option for damaged CF lungs , but unfortunately it is not a cure for CF.


Denis Pearce   |   Member since 2009  |  ✔ Verified

Can you develop cystic fibrosis or are you born with it?

As with other genetic conditions, cystic fibrosis will have been present since birth, even if it is diagnosed later in life. One in 25 people carry the faulty gene that causes cystic fibrosis . To have cystic fibrosis , both parents must be carriers of the faulty cystic fibrosis gene.


Iris Williams   |   Member since 2009  |  ✔ Verified

Why do CF patients have to stay 5 feet apart?

That's why it's important for people with CF to stay at least 6 feet away from others with CF and anyone with a cold, flu, or infection. For people with CF , being close to others with the disease puts them at greater risk of getting and spreading dangerous germs and bacteria. This is called cross-infection.


Chuck Murray   |   Member since 2010  |  ✔ Verified

How does a child get cystic fibrosis?

The gene that causes cystic fibrosis is recessive. This means that in order to have cystic fibrosis , children must inherit two copies of the gene, one from each parent. If a child inherits only one copy, he or she won't develop cystic fibrosis .


Logan Cowan   |   Member since 2016  |  ✔ Verified

Why does cystic fibrosis skip generations?

Because the disease is recessive, it can skip several generations . Cystic fibrosis affects the lungs. To predict how many offspring will have a particular genotype you use a Punnett square. For example in cystic fibrosis if both parents are heterozygous, each child has a 25% chance of being born with cystic fibrosis .


Henry Kidd   |   Member since 2017  |  ✔ Verified

At what age is cystic fibrosis usually diagnosed?

Most children are now screened for CF at birth through newborn screening and the majority are diagnosed by age 2. However, some people with CF are diagnosed as adults. A doctor who sees the symptoms of CF will order a sweat test and a genetic test to confirm the diagnosis .


Benny Milner   |   Member since 2012  |  ✔ Verified

What is the first sign of cystic fibrosis?

Early signs of CF include: Salty sweat; many parents notice a salty taste when kissing their child. Poor growth and weight gain (failure to thrive) Constant coughing and wheezing.


Russel Thorne   |   Member since 2014  |  ✔ Verified

How common is it to be a carrier of cystic fibrosis?

About one in every 35 Americans is a symptomless carrier of the defective CFTR gene. Only about one of every 3, 000 Caucasian newborns has CF . We know there are more than 1, 700 mutations of the CFTR gene.


David Quinn   |   Member since 2014  |  ✔ Verified

Can siblings with cystic fibrosis live together?

Brother and sister with cystic fibrosis could pass on life-threatening infections to each other. These siblings just love to play together - but their mother has to keep a watchful eye on them in case they give each other life-threatening infections.


Louise Taylor   |   Member since 2013  |  ✔ Verified

How is cystic fibrosis transmitted?

Cystic Fibrosis is transmitted in an autosomal resave manner. Both parents must have the defective gene and pass it to their offspring to have a child with cystic fibrosis . Children with CF in the same family may have varying degrees of the disease.


Javier Rogers   |   Member since 2018  |  ✔ Verified

Can a child have CF if only one parent is a carrier?

Children may be born with cystic fibrosis if each parent carries one faulty gene for the disease. Someone with one normal CF gene and one faulty CF gene is known as a cystic fibrosis carrier . You can be a carrier and not have the disease yourself.


Samantha Rossi   |   Member since 2012  |  ✔ Verified

Which parent has the dominant gene?

If a gene version is dominant, it will dominate whether it came from mom or dad. So your chances of getting a dominant trait don't depend on which parent it came from. If mom gives you the dominant brown eye version of an eye color gene, odds are you'll end up with brown eyes. Same thing if dad passes the same gene.


Hailey Uddin   |   Member since 2020  |  ✔ Verified

What race is cystic fibrosis most common in?

Although cystic fibrosis is more commonly found in the white population, the disease affects all racial groups. Cystic fibrosis occurs in about one in every 3, 500 white births, one in every 17, 000 black births, and one in every 90, 000 Asian births.


Harry Rehman   |   Member since 2020  |  ✔ Verified

Can your baby have cystic fibrosis If you are not a carrier?

Carriers for CF have no symptoms, but can pass the non-functioning gene on to their children. If both parents are carriers there is a 1 in 4 (25 percent) chance that both will pass on the non-functioning gene, which would result in a pregnancy affected with cystic fibrosis .


Percy Price   |   Member since 2011  |  ✔ Verified

How is hemophilia inherited?

Hemophilia A and hemophilia B are inherited in an X-linked recessive pattern. The genes associated with these conditions are located on the X chromosome, which is one of the two sex chromosomes. In females (who have two X chromosomes), a mutation would have to occur in both copies of the gene to cause the disorder.


Ada Gilbert   |   Member since 2005  |  ✔ Verified

What is cystic fibrosis life expectancy?

The average life expectancy of a person with cystic fibrosis in the U.S. is approximately 37.5 years with many living much longer. However, this figure is constantly increasing as researchers discover new treatments and medications.


Aiden Fowler   |   Member since 2020  |  ✔ Verified

Which organs are affected by cystic fibrosis?

Cystic fibrosis is a condition which mainly affects the lungs and pancreas but can affect other parts of the body, including the liver, nose and sinuses and sweat glands. Normally, cells in these parts of the body make mucus and other watery juices and secretions.


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